Cancer cell-soluble factors reprogram mesenchymal stromal cells to slow cycling, chemoresistant cells with a more stem-like state

BACKGROUND: Mesenchymal stem cells (MSCs) play different roles in modulating tumor progression, growth, and metastasis. MSCs are recruited to the tumor site in large numbers and subsequently have an important microenvironmental role in modulating tumor progression and drug sensitivity. However, the...

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Detalles Bibliográficos
Publicado en:Stem Cell Res Ther
Autores principales: El-Badawy, Ahmed, Ghoneim, Mohamed A., Gabr, Mahmoud M., Salah, Radwa Ayman, Mohamed, Ihab K., Amer, Marwa, El-Badri, Nagwa
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688803/
https://ncbi.nlm.nih.gov/pubmed/29115987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0709-9
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