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A novel GIT2-BRAF fusion in pilocytic astrocytoma

BACKGROUND: KIAA1549-BRAF fusion is the most common genetic event in pilocytic astrocytoma (PA), and leads to activation of the mitogen activated protein kinase (MAPK) signaling pathway. Fusions of BRAF with other partner genes, as well as other genetic alterations not involving BRAF but also leadin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Diagn Pathol
Hauptverfasser: Helgager, Jeffrey, Lidov, Hart G., Mahadevan, Navin R., Kieran, Mark W., Ligon, Keith L., Alexandrescu, Sanda
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688665/
https://ncbi.nlm.nih.gov/pubmed/29141672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-017-0669-5
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