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Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas

Brain tumours are the commonest solid tumours of childhood, and pilocytic astrocytomas (PAs) are the most common central nervous system tumour in 5-19 year-olds. Little is known about the genetic alterations underlying their development. Here we describe a tandem duplication of ∼2Mb at 7q34 occurrin...

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Detalhes bibliográficos
Main Authors: Jones, David T. W., Kocialkowski, Sylvia, Liu, Lu, Pearson, Danita M., Bäcklund, L. Magnus, Ichimura, Koichi, Collins, V. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577184/
https://ncbi.nlm.nih.gov/pubmed/18974108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2097
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