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A novel GIT2-BRAF fusion in pilocytic astrocytoma

BACKGROUND: KIAA1549-BRAF fusion is the most common genetic event in pilocytic astrocytoma (PA), and leads to activation of the mitogen activated protein kinase (MAPK) signaling pathway. Fusions of BRAF with other partner genes, as well as other genetic alterations not involving BRAF but also leadin...

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Publicado en:Diagn Pathol
Autores principales: Helgager, Jeffrey, Lidov, Hart G., Mahadevan, Navin R., Kieran, Mark W., Ligon, Keith L., Alexandrescu, Sanda
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688665/
https://ncbi.nlm.nih.gov/pubmed/29141672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-017-0669-5
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