Structural basis for tRNA-dependent cysteine biosynthesis

Cysteine can be synthesized by tRNA-dependent mechanism using a two-step indirect pathway, where O-phosphoseryl-tRNA synthetase (SepRS) catalyzes the ligation of a mismatching O-phosphoserine (Sep) to tRNA(Cys) followed by the conversion of tRNA-bounded Sep into cysteine by Sep-tRNA:Cys-tRNA synthas...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Chen, Meirong, Kato, Koji, Kubo, Yume, Tanaka, Yoshikazu, Liu, Yuchen, Long, Feng, Whitman, William B., Lill, Pascal, Gatsogiannis, Christos, Raunser, Stefan, Shimizu, Nobutaka, Shinoda, Akira, Nakamura, Akiyoshi, Tanaka, Isao, Yao, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688128/
https://ncbi.nlm.nih.gov/pubmed/29142195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01543-y
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