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Structure of the Pseudomonas aeruginosa transamidosome reveals unique aspects of bacterial tRNA-dependent asparagine biosynthesis

Many prokaryotes lack a tRNA synthetase to attach asparagine to its cognate tRNA(Asn), and instead synthesize asparagine from tRNA(Asn)-bound aspartate. This conversion involves two enzymes: a nondiscriminating aspartyl-tRNA synthetase (ND-AspRS) that forms Asp-tRNA(Asn), and a heterotrimeric amidot...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Suzuki, Tateki, Nakamura, Akiyoshi, Kato, Koji, Söll, Dieter, Tanaka, Isao, Sheppard, Kelly, Yao, Min
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299244/
https://ncbi.nlm.nih.gov/pubmed/25548166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423314112
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