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Ancient translation factor is essential for tRNA-dependent cysteine biosynthesis in methanogenic archaea

Methanogenic archaea lack cysteinyl-tRNA synthetase; they synthesize Cys-tRNA and cysteine in a tRNA-dependent manner. Two enzymes are required: Phosphoseryl-tRNA synthetase (SepRS) forms phosphoseryl-tRNA(Cys) (Sep-tRNA(Cys)), which is converted to Cys-tRNA(Cys) by Sep-tRNA:Cys-tRNA synthase (SepCy...

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Hlavní autoři: Liu, Yuchen, Nakamura, Akiyoshi, Nakazawa, Yuto, Asano, Nozomi, Ford, Kara A., Hohn, Michael J., Tanaka, Isao, Yao, Min, Söll, Dieter
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115501/
https://ncbi.nlm.nih.gov/pubmed/25002468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411267111
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