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Partners in Crime: Phenolic Glycolipids and Macrophages

Two recent articles advance our understanding of mycobacterial pathogenesis, revealing key roles for bacterial-derived phenolic glycolipids (PGL). In leprosy, Mycobacterium leprae’s PGL-1 uniquely subverts local macrophages to produce neurotoxic nitric oxide, leading to nerve demyelination. In a rel...

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Detalhes bibliográficos
Publicado no:Trends Mol Med
Main Authors: Singh, Alok Kumar, Bishai, William R
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687990/
https://ncbi.nlm.nih.gov/pubmed/28969977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2017.09.003
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