A Macrophage Response to Mycobacterium leprae Phenolic Glycolipid Initiates Nerve Damage in Leprosy

Mycobacterium leprae causes leprosy and is unique among mycobacterial diseases in producing peripheral neuropathy. This debilitating morbidity is attributed to axon demyelination resulting from direct interaction of the M. leprae-specific phenolic glycolipid 1 (PGL-1) with myelinating glia and their...

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Vydáno v:Cell
Hlavní autoři: Madigan, Cressida A., Cambier, C.J., Kelly-Scumpia, Kindra M., Scumpia, Philip O., Cheng, Tan-Yun, Zailaa, Joseph, Bloom, Barry R., Moody, D. Branch, Smale, Stephen T., Sagasti, Alvaro, Modlin, Robert L., Ramakrishnan, Lalita
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848073/
https://ncbi.nlm.nih.gov/pubmed/28841420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.030
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