A Macrophage Response to Mycobacterium leprae Phenolic Glycolipid Initiates Nerve Damage in Leprosy

Mycobacterium leprae causes leprosy and is unique among mycobacterial diseases in producing peripheral neuropathy. This debilitating morbidity is attributed to axon demyelination resulting from direct interaction of the M. leprae-specific phenolic glycolipid 1 (PGL-1) with myelinating glia and their...

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Sparad:
Bibliografiska uppgifter
I publikationen:Cell
Huvudupphovsmän: Madigan, Cressida A., Cambier, C.J., Kelly-Scumpia, Kindra M., Scumpia, Philip O., Cheng, Tan-Yun, Zailaa, Joseph, Bloom, Barry R., Moody, D. Branch, Smale, Stephen T., Sagasti, Alvaro, Modlin, Robert L., Ramakrishnan, Lalita
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cell Press 2017
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848073/
https://ncbi.nlm.nih.gov/pubmed/28841420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.030
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