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Integrative epigenetic and genetic pan-cancer somatic alteration portraits
Genetic and epigenetic alterations are required for carcinogenesis and the mutation burden across tumor types has been investigated. Here, we investigate epigenetic alterations with a novel measure of global DNA methylation dysregulation, the methylation dysregulation index (MDI), across 14 cancer t...
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| Vydáno v: | Epigenetics |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5687331/ https://ncbi.nlm.nih.gov/pubmed/28426276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1319043 |
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