Integrative epigenetic and genetic pan-cancer somatic alteration portraits

Genetic and epigenetic alterations are required for carcinogenesis and the mutation burden across tumor types has been investigated. Here, we investigate epigenetic alterations with a novel measure of global DNA methylation dysregulation, the methylation dysregulation index (MDI), across 14 cancer t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Epigenetics
Prif Awduron: Salas, Lucas A., Johnson, Kevin C., Koestler, Devin C., O'Sullivan, Dylan E., Christensen, Brock C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2017
Pynciau:
Research Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687331/
https://ncbi.nlm.nih.gov/pubmed/28426276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1319043
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