Genome-Wide Mutagenesis of Dengue Virus Reveals Plasticity of the NS1 Protein and Enables Generation of Infectious Tagged Reporter Viruses

Dengue virus (DENV) is a major global pathogen that causes significant morbidity and mortality in tropical and subtropical areas worldwide. An improved understanding of the regions within the DENV genome and its encoded proteins that are required for the virus replication cycle will expedite the dev...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Eyre, Nicholas S., Johnson, Stephen M., Eltahla, Auda A., Aloi, Maria, Aloia, Amanda L., McDevitt, Christopher A., Bull, Rowena A., Beard, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686748/
https://ncbi.nlm.nih.gov/pubmed/28956770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01455-17
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