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Mutagenesis of Dengue Virus Protein NS2A Revealed a Novel Domain Responsible for Virus-Induced Cytopathic Effect and Interactions between NS2A and NS2B Transmembrane Segments

The NS2A protein of dengue virus (DENV) has eight predicted transmembrane segments (pTMS1 to -8) and participates in RNA replication, virion assembly, and host antiviral response. However, the roles of specific amino acid residues within the pTMS regions of NS2A during the viral life cycle are not c...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Virol
Κύριοι συγγραφείς: Wu, Ren-Huang, Tsai, Ming-Han, Tsai, Kuen-Nan, Tian, Jia Ni, Wu, Jian-Sung, Wu, Su-Ying, Chern, Jyh-Haur, Chen, Chun-Hong, Yueh, Andrew
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446631/
https://ncbi.nlm.nih.gov/pubmed/28381578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01836-16
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