Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection

Inhibitory receptors have been extensively described for their importance in regulating immune responses in chronic infections and cancers. Blocking the function of inhibitory receptors such as PD-1, CTLA-4, 2B4, Tim-3, and LAG-3 has shown promise for augmenting CD8 T cell activity and boosting path...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Teigler, Jeffrey E., Zelinskyy, Gennadiy, Eller, Michael A., Bolton, Diane L., Marovich, Mary, Gordon, Alexander D., Alrubayyi, Aljawharah, Alter, Galit, Robb, Merlin L., Martin, Jeffrey N., Deeks, Steven G., Michael, Nelson L., Dittmer, Ulf, Streeck, Hendrik
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686724/
https://ncbi.nlm.nih.gov/pubmed/28904197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01263-17
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