Production of HIV-1 Env-Specific Antibodies Mediating Innate Immune Functions Depends on Cognate Interleukin-21- Secreting CD4(+) T Cells

Antibodies with a functional Fc region were previously associated with protection from HIV-1 acquisition and spontaneous suppression of viral replication. Unlike broadly neutralizing antibodies, they are not restricted to neutralizing epitopes and do not require unconventional structural traits to e...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Pušnik, Jernej, Fischinger, Stephanie, Dittmer, Ulf, Esser, Stefan, van Gils, Marit J., Sanders, Rogier W., Alter, Galit, Streeck, Hendrik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103692/
https://ncbi.nlm.nih.gov/pubmed/33504598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02097-20
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