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Chromatin remodeler CHD1 promotes XPC‐to‐TFIIH handover of nucleosomal UV lesions in nucleotide excision repair

Ultraviolet (UV) light induces mutagenic cyclobutane pyrimidine dimers (CPDs) in nucleosomal DNA that is tightly wrapped around histone octamers. How global‐genome nucleotide excision repair (GG‐NER) processes CPDs despite that this chromatin arrangement is poorly understood. An increased chromatin...

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書目詳細資料
發表在:EMBO J
Main Authors: Rüthemann, Peter, Balbo Pogliano, Chiara, Codilupi, Tamara, Garajovà, Zuzana, Naegeli, Hanspeter
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686551/
https://ncbi.nlm.nih.gov/pubmed/29018037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695742
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