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Poly(ADP-ribose) polymerase 1 escorts XPC to UV-induced DNA lesions during nucleotide excision repair

Xeroderma pigmentosum C (XPC) protein initiates the global genomic subpathway of nucleotide excision repair (GG-NER) for removal of UV-induced direct photolesions from genomic DNA. The XPC has an inherent capacity to identify and stabilize at the DNA lesion sites, and this function is facilitated in...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Robu, Mihaela, Shah, Rashmi G., Purohit, Nupur K., Zhou, Pengbo, Naegeli, Hanspeter, Shah, Girish M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565455/
https://ncbi.nlm.nih.gov/pubmed/28760956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706981114
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