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Role of poly(ADP-ribose) polymerase-1 in the removal of UV-induced DNA lesions by nucleotide excision repair

Among the earliest responses of mammalian cells to DNA damage is catalytic activation of a nuclear enzyme poly(ADP-ribose) polymerase-1 (PARP-1). Activated PARP-1 forms the polymers of ADP-ribose (pADPr or PAR) that posttranslationally modify its target proteins, such as PARP-1 and DNA repair–relate...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Robu, Mihaela, Shah, Rashmi G., Petitclerc, Nancy, Brind’Amour, Julie, Kandan-Kulangara, Febitha, Shah, Girish M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562836/
https://ncbi.nlm.nih.gov/pubmed/23319653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209507110
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