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Combinatorial regulation of the balance between dynein microtubule end accumulation and initiation of directed motility

Cytoplasmic dynein is involved in a multitude of essential cellular functions. Dynein's activity is controlled by the combinatorial action of several regulatory proteins. The molecular mechanism of this regulation is still poorly understood. Using purified proteins, we reconstitute the regulati...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Jha, Rupam, Roostalu, Johanna, Cade, Nicholas I, Trokter, Martina, Surrey, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686545/
https://ncbi.nlm.nih.gov/pubmed/29038173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797077
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