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Combinatorial regulation of the balance between dynein microtubule end accumulation and initiation of directed motility

Cytoplasmic dynein is involved in a multitude of essential cellular functions. Dynein's activity is controlled by the combinatorial action of several regulatory proteins. The molecular mechanism of this regulation is still poorly understood. Using purified proteins, we reconstitute the regulati...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Jha, Rupam, Roostalu, Johanna, Cade, Nicholas I, Trokter, Martina, Surrey, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686545/
https://ncbi.nlm.nih.gov/pubmed/29038173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797077
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