Predictors of Naltrexone Response in a Randomized Trial: Reward-Related Brain Activation, OPRM1 Genotype, and Smoking Status

Naltrexone reduces drinking among individuals with alcohol use disorders (AUDs), but it is not effective for everyone. Variability in its effects on reward-related brain activation, genetic variation, and/or cigarette smoking may account for this mixed response profile. This randomized clinical tria...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Schacht, Joseph P, Randall, Patrick K, Latham, Patricia K, Voronin, Konstantin E, Book, Sarah W, Myrick, Hugh, Anton, Raymond F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686497/
https://ncbi.nlm.nih.gov/pubmed/28409564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.74
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