Interacting Effects of Naltrexone and OPRM1 and DAT1 Variation on the Neural Response to Alcohol Cues

Variation at a single nucleotide polymorphism in the μ-opioid receptor gene (OPRM1), A118G (Asn40Asp), may moderate naltrexone (NTX) effects in alcohol dependence. Both NTX and A118G variation have also been reported to affect alcohol cue-elicited brain activation. This study investigated whether su...

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Detalhes bibliográficos
Main Authors: Schacht, Joseph P, Anton, Raymond F, Voronin, Konstantin E, Randall, Patrick K, Li, Xingbao, Henderson, Scott, Myrick, Hugh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547192/
https://ncbi.nlm.nih.gov/pubmed/23032071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.195
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