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Dopaminergic Genetic Variation Influences Aripiprazole Effects on Alcohol Self-Administration and the Neural Response to Alcohol Cues in a Randomized Trial

Dopamine (DA) signaling regulates many aspects of Alcohol Use Disorder (AUD). However, clinical studies of dopaminergic medications, including the DA partial agonist aripiprazole (APZ), have been inconsistent, suggesting the possibility of a pharmacogenetic interaction. This study examined whether v...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Schacht, Joseph P, Voronin, Konstantin E, Randall, Patrick K, Anton, Raymond F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916367/
https://ncbi.nlm.nih.gov/pubmed/29362512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.298
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