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Aurora kinase A inhibitor TCS7010 demonstrates pro-apoptotic effect through the unfolded protein response pathway in HCT116 colon cancer cells

Aurora kinase A (AURKA) is essential for regulating mitosis and is frequently amplified in various cancer cell types. However, the effect of AURKA inhibition on the induction of apoptosis remains unclear. In the present study, it was reported that treatment with TCS7010, a specific inhibitor of AURK...

詳細記述

保存先:
書誌詳細
出版年:Oncol Lett
主要な著者: Lee, Da Hyun, Kim, Chang Gun, Lim, Yoongho, Shin, Soon Young
フォーマット: Artigo
言語:Inglês
出版事項: D.A. Spandidos 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686436/
https://ncbi.nlm.nih.gov/pubmed/29163689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7023
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