Post-translational regulation of p53 function through 20S proteasome-mediated cleavage

The tumor suppressor p53 is a transcription factor that regulates the expression of a range of target genes in response to cellular stress. Adding to the complexity of understanding its cellular function is that in addition to the full-length protein, several p53 isoforms are produced in humans, har...

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Publicat a:Cell Death Differ
Autors principals: Solomon, Hilla, Bräuning, Bastian, Fainer, Irit, Ben-Nissan, Gili, Rabani, Stav, Goldfinger, Naomi, Moscovitz, Oren, Shakked, Zippora, Rotter, Varda, Sharon, Michal
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686354/
https://ncbi.nlm.nih.gov/pubmed/28885617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.139
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