Mnt modulates Myc-driven lymphomagenesis

The transcriptional represser Mnt is a functional antagonist of the proto-oncoprotein Myc. Both Mnt and Myc utilise Max as an obligate partner for DNA binding, and Myc/Max and Mnt/Max complexes compete for occupancy at E-box DNA sequences in promoter regions. We have previously shown in transgenic m...

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Publicat a:Cell Death Differ
Autors principals: Campbell, Kirsteen J, Vandenberg, Cassandra J, Anstee, Natasha S, Hurlin, Peter J, Cory, Suzanne
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686348/
https://ncbi.nlm.nih.gov/pubmed/28800127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.131
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