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PKPD modeling of acquired resistance to anti-cancer drug treatment
Non-small cell lung cancer (NSCLC) patients greatly benefit from the treatment with tyrosine kinase inhibitors (TKIs) targeting the epidermal growth factor receptor (EGFR). However, emergence of acquired resistance inevitable occurs after long-term treatment in most patients and limits clinical impr...
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| Publicado no: | J Pharmacokinet Pharmacodyn |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5686279/ https://ncbi.nlm.nih.gov/pubmed/29090407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-017-9553-x |
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