Recent developments in using mechanistic cardiac modelling for drug safety evaluation

On the tenth anniversary of two key International Conference on Harmonisation (ICH) guidelines relating to cardiac proarrhythmic safety, an initiative aims to consider the implementation of a new paradigm that combines in vitro and in silico technologies to improve risk assessment. The Comprehensive...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Drug Discov Today
Päätekijät: Davies, Mark R., Wang, Ken, Mirams, Gary R., Caruso, Antonello, Noble, Denis, Walz, Antje, Lavé, Thierry, Schuler, Franz, Singer, Thomas, Polonchuk, Liudmila
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier Science Ltd. ;, Distributed by Virgin Mailing and Distribution 2016
Aiheet:
Review
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909717/
https://ncbi.nlm.nih.gov/pubmed/26891981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2016.02.003
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