Llwytho...

The Semaphorin 3A inhibitor SM-345431 preserves corneal nerve and epithelial integrity in a murine dry eye model

Dry eye disease (DED) is a common disorder causing discomfort and ocular fatigue. Corneal nerves are compromised in DED, which may further cause loss of corneal sensation and decreased tear secretion. Semaphorin 3A (Sema3A) is expressed by the corneal epithelium under stress, and is known as an inhi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Yamazaki, Risa, Yamazoe, Katsuya, Yoshida, Satoru, Hatou, Shin, Inagaki, Emi, Okano, Hideyuki, Tsubota, Kazuo, Shimmura, Shigeto
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686158/
https://ncbi.nlm.nih.gov/pubmed/29138447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15682-1
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