The Semaphorin 3A Inhibitor SM-345431 Accelerates Peripheral Nerve Regeneration and Sensitivity in a Murine Corneal Transplantation Model

BACKGROUND: Peripheral nerve damage of the cornea is a complication following surgery or infection which may lead to decreased visual function. We examined the efficacy of the semaphorin 3A inhibitor, SM-345431, in promoting regeneration of peripheral nerves in a mouse corneal transplantation model....

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Detalhes bibliográficos
Main Authors: Omoto, Masahiro, Yoshida, Satoru, Miyashita, Hideyuki, Kawakita, Tetsuya, Yoshida, Kenji, Kishino, Akiyoshi, Kimura, Toru, Shibata, Shinsuke, Tsubota, Kazuo, Okano, Hideyuki, Shimmura, Shigeto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494696/
https://ncbi.nlm.nih.gov/pubmed/23152758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047716
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