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Long-term homeostasis and wound healing in an in vitro epithelial stem cell niche model

Cultures of epithelial cells are limited by the proliferative capacity of primary cells and cell senescence. Herein we show that primary human epithelial cell sheets cultured without dermal equivalents maintained homeostasis in vitro for at least 1 year. Transparency of these sheets enabled live obs...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Miyashita, Hideyuki, Niwano, Hiroko, Yoshida, Satoru, Hatou, Shin, Inagaki, Emi, Tsubota, Kazuo, Shimmura, Shigeto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324070/
https://ncbi.nlm.nih.gov/pubmed/28233843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43557
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