YAP1 is essential for tumor growth and is a potential therapeutic target for EGFR-dependent lung adenocarcinomas

Epidermal growth factor receptor (EGFR) mutations are found in lung adenocarcinomas leading to tumor cells proliferation and survival. EGFR tyrosine kinase inhibitors (TKIs) that block EGFR activity are effective therapeutics for EGFR-mutant lung adenocarcinoma patients, but TKI-resistance inevitabl...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lee, Ting-Fang, Tseng, Yu-Chi, Chang, Wei-Chin, Chen, Yi-Chen, Kao, Yu-Rung, Chou, Teh-Ying, Ho, Chao-Chi, Wu, Cheng-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685690/
https://ncbi.nlm.nih.gov/pubmed/29163769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19647
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