YAP1 is essential for tumor growth and is a potential therapeutic target for EGFR-dependent lung adenocarcinomas

Epidermal growth factor receptor (EGFR) mutations are found in lung adenocarcinomas leading to tumor cells proliferation and survival. EGFR tyrosine kinase inhibitors (TKIs) that block EGFR activity are effective therapeutics for EGFR-mutant lung adenocarcinoma patients, but TKI-resistance inevitabl...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Lee, Ting-Fang, Tseng, Yu-Chi, Chang, Wei-Chin, Chen, Yi-Chen, Kao, Yu-Rung, Chou, Teh-Ying, Ho, Chao-Chi, Wu, Cheng-Wen
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685690/
https://ncbi.nlm.nih.gov/pubmed/29163769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19647
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