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PD-L1 expression and CD8+ tumor-infiltrating lymphocytes are associated with ALK rearrangement and clinicopathological features in inflammatory myofibroblastic tumors

BACKGROUND: Inflammatory myofibroblastic tumors (IMTs) are rare mesenchymal neoplasms that are composed of myofibroblastic cells accompanied by inflammatory infiltrate. We investigated the immune profiles of IMTs, including PD-L1 expression and proportion of CD8+ tumor-infiltrating lymphocytes (TILs...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Cha, Yoon Jin, Shim, Hyo Sup
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685684/
https://ncbi.nlm.nih.gov/pubmed/29163763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20948
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