Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab

The mechanisms by which immune checkpoint blockade modulates tumor evolution during therapy are unclear. We assessed genomic changes in tumors from 68 patients with advanced melanoma, who progressed on ipilimumab or were ipilimumab-naive, before and after nivolumab initiation (CA209-038 study). Tumo...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell
Egile Nagusiak: Riaz, Nadeem, Havel, Jonathan J., Makarov, Vladimir, Desrichard, Alexis, Urba, Walter J., Sims, Jennifer S., Hodi, F. Stephen, Martín-Algarra, Salvador, Mandal, Rajarsi, Sharfman, William H., Bhatia, Shailender, Hwu, Wen-Jen, Gajewski, Thomas F., Slingluff, Craig L., Chowell, Diego, Kendall, Sviatoslav M., Chang, Han, Shah, Rachna, Kuo, Fengshen, Morris, Luc G.T., Sidhom, John-William, Schneck, Jonathan P., Horak, Christine E., Weinhold, Nils, Chan, Timothy A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685550/
https://ncbi.nlm.nih.gov/pubmed/29033130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.028
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