Neurologic Serious Adverse Events Associated with Nivolumab Plus Ipilimumab or Nivolumab Alone in Advanced Melanoma, Including a Case Series of Encephalitis

BACKGROUND. Despite unprecedented efficacy across multiple tumor types, immune checkpoint inhibitor therapy is associated with a unique and wide spectrum of immune‐related adverse events (irAEs), including neurologic events ranging from mild headache to potentially life‐threatening encephalitis. Her...

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Vydáno v:Oncologist
Hlavní autoři: Larkin, James, Chmielowski, Bartosz, Lao, Christopher D., Hodi, F. Stephen, Sharfman, William, Weber, Jeffrey, Suijkerbuijk, Karijn P. M., Azevedo, Sergio, Li, Hewei, Reshef, Daniel, Avila, Alexandre, Reardon, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: AlphaMed Press 2017
Témata:
Melanoma and Cutaneous Malignancies
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469590/
https://ncbi.nlm.nih.gov/pubmed/28495807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2016-0487
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