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Extracellular vesicles of bone marrow stromal cells rescue chronic lymphocytic leukemia B cells from apoptosis, enhance their migration and induce gene expression modifications

Interactions between chronic lymphocytic leukemia (CLL) B cells and the bone marrow (BM) microenvironment play a major function in the physiopathology of CLL. Extracellular vesicles (EVs), which are composed of exosomes and microparticles, play an important role in cell communication. However, littl...

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Vydáno v:Haematologica
Hlavní autoři: Crompot, Emerence, Van Damme, Michael, Pieters, Karlien, Vermeersch, Marjorie, Perez-Morga, David, Mineur, Philippe, Maerevoet, Marie, Meuleman, Nathalie, Bron, Dominique, Lagneaux, Laurence, Stamatopoulos, Basile
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685228/
https://ncbi.nlm.nih.gov/pubmed/28596280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.163337
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