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Impaired mitochondrial calcium uptake caused by tacrolimus underlies beta-cell failure
BACKGROUND: One of the most common side effects of the immunosuppressive drug tacrolimus (FK506) is the increased risk of new-onset diabetes mellitus. However, the molecular mechanisms underlying this association have not been fully clarified. METHODS: We studied the effects of the therapeutic dose...
Shranjeno v:
| izdano v: | Cell Commun Signal |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5684747/ https://ncbi.nlm.nih.gov/pubmed/29132395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-017-0203-0 |
| Oznake: |
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