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Impaired mitochondrial calcium uptake caused by tacrolimus underlies beta-cell failure
BACKGROUND: One of the most common side effects of the immunosuppressive drug tacrolimus (FK506) is the increased risk of new-onset diabetes mellitus. However, the molecular mechanisms underlying this association have not been fully clarified. METHODS: We studied the effects of the therapeutic dose...
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| 發表在: | Cell Commun Signal |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5684747/ https://ncbi.nlm.nih.gov/pubmed/29132395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-017-0203-0 |
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