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Exposure to High Glucose Concentration Decreases Cell Surface ABCA1 and HDL Biogenesis in Hepatocytes

Aim: To study atherosclerosis risk in diabetes, we investigated ATP-binding cassette transporter A1 (ABCA1) expression and high-density lipoprotein (HDL) biogenesis in the liver and hepatocytes under hyperglycemic conditions. Methods and Results: In streptozotocin-induced diabetic mice, plasma HDL d...

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Detalhes bibliográficos
Publicado no:J Atheroscler Thromb
Main Authors: Tsujita, Maki, Hossain, Mohammad Anwar, Lu, Rui, Tsuboi, Tomoe, Okumura-Noji, Kuniko, Yokoyama, Shinji
Formato: Artigo
Idioma:Inglês
Publicado em: Japan Atherosclerosis Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684479/
https://ncbi.nlm.nih.gov/pubmed/28428480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5551/jat.39156
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