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ABCA1-dependent sterol release: sterol molecule specificity and potential membrane domain for HDL biogenesis
Mammalian cells synthesize various sterol molecules, including the C30 sterol, lanosterol, as cholesterol precursors in the endoplasmic reticulum. The build-up of precursor sterols, including lanosterol, displays cellular toxicity. Precursor sterols are found in plasma HDL. How these structurally di...
Gardado en:
| Publicado en: | J Lipid Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4689340/ https://ncbi.nlm.nih.gov/pubmed/26497474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M063784 |
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