Deficiency in the Lipid Exporter ABCA1 Impairs Retrograde Sterol Movement and Disrupts Sterol Sensing at the Endoplasmic Reticulum

Cellular cholesterol homeostasis involves sterol sensing at the endoplasmic reticulum (ER) and sterol export from the plasma membrane (PM). Sterol sensing at the ER requires efficient sterol delivery from the PM; however, the macromolecules that facilitate retrograde sterol transport at the PM have...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yamauchi, Yoshio, Iwamoto, Noriyuki, Rogers, Maximillian A., Abe-Dohmae, Sumiko, Fujimoto, Toyoshi, Chang, Catherine C. Y., Ishigami, Masato, Kishimoto, Takuma, Kobayashi, Toshihide, Ueda, Kazumitsu, Furukawa, Koichi, Chang, Ta-Yuan, Yokoyama, Shinji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583027/
https://ncbi.nlm.nih.gov/pubmed/26198636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.662668
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