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Apelin conformational and binding equilibria upon micelle interaction primarily depend on membrane-mimetic headgroup
Apelin is one of two peptide hormones that activate the apelin receptor (AR or APJ) to regulate the cardiovascular system, central nervous system, and adipoinsular axis. Here, we apply circular dichroism (CD) spectropolarimetry and nuclear magnetic resonance (NMR) spectroscopy to characterize the po...
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| Udgivet i: | Sci Rep |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5684411/ https://ncbi.nlm.nih.gov/pubmed/29133807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14784-0 |
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