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Divergent roles for Clusterin in Lung Injury and Repair

Lung fibrosis is an unabated wound healing response characterized by the loss and aberrant function of lung epithelial cells. Herein, we report that extracellular Clusterin promoted epithelial cell apoptosis whereas intracellular Clusterin maintained epithelium viability during lung repair. Unlike n...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Habiel, David M., Camelo, Ana, Espindola, Milena, Burwell, Timothy, Hanna, Richard, Miranda, Elena, Carruthers, Alan, Bell, Matthew, Coelho, Ana Lucia, Liu, Hao, Pilataxi, Fernanda, Clarke, Lori, Grant, Ethan, Lewis, Arthur, Moore, Bethany, Knight, Darryl A., Hogaboam, Cory M., Murray, Lynne A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684342/
https://ncbi.nlm.nih.gov/pubmed/29133960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15670-5
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