Role of MicroRNA-143 in Nerve Injury-Induced Upregulation of Dnmt3a Expression in Primary Sensory Neurons

Peripheral nerve injury increased the expression of the DNA methyltransferase 3A (Dnmt3a) mRNA and its encoding Dnmt3a protein in injured dorsal root ganglia (DRG). This increase is considered as an endogenous instigator in neuropathic pain genesis through epigenetic silencing of pain-associated gen...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Xu, Bo, Cao, Jing, Zhang, Jun, Jia, Shushan, Wu, Shaogen, Mo, Kai, Wei, Guihua, Liang, Lingli, Miao, Xuerong, Bekker, Alex, Tao, Yuan-Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684171/
https://ncbi.nlm.nih.gov/pubmed/29170626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00350
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