mTOR intersects antibody-inducing signals from TACI in marginal zone B cells

Mechanistic target of rapamycin (mTOR) enhances immunity in addition to orchestrating metabolism. Here we show that mTOR coordinates immunometabolic reconfiguration of marginal zone (MZ) B cells, a pre-activated lymphocyte subset that mounts antibody responses to T-cell-independent antigens through...

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מידע ביבליוגרפי
הוצא לאור ב:Nat Commun
Main Authors: Sintes, Jordi, Gentile, Maurizio, Zhang, Shuling, Garcia-Carmona, Yolanda, Magri, Giuliana, Cassis, Linda, Segura-Garzón, Daniel, Ciociola, Alessandra, Grasset, Emilie K., Bascones, Sabrina, Comerma, Laura, Pybus, Marc, Lligé, David, Puga, Irene, Gutzeit, Cindy, He, Bing, DuBois, Wendy, Crespo, Marta, Pascual, Julio, Mensa, Anna, Aróstegui, Juan Ignacio, Juan, Manel, Yagüe, Jordi, Serrano, Sergi, Lloreta, Josep, Meffre, Eric, Hahne, Michael, Cunningham-Rundles, Charlotte, Mock, Beverly A., Cerutti, Andrea
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2017
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684130/
https://ncbi.nlm.nih.gov/pubmed/29133782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01602-4
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