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TRiC/CCT chaperonins are essential for maintaining myofibril organization, cardiac physiological rhythm, and life span

We recently reported that CCT chaperonin subunits are upregulated in a cardiac-specific manner under time-restricted feeding (TRF) (Gill et al. Science 2015, 347:1265–9), suggesting that TRiC/CCT has a heart-specific function. To understand the CCT chaperonin function in cardiomyocytes, we performed...

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Publicado en:FEBS Lett
Autores principales: Melkani, Girish C., Bhide, Shruti, Han, Andrew, Vyas, Jay, Livelo, Catherine, Bodmer, Rolf, Bernstein, Sanford I.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5683924/
https://ncbi.nlm.nih.gov/pubmed/28963798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12860
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