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Structure Optimization of Aloperine Derivatives as HIV-1 Entry Inhibitors
[Image: see text] As a step toward developing novel anti-HIV agents, we have identified a class of quinolizidines, including aloperine, that inhibit HIV at 1–5 μM by blocking viral entry. In this study, we have optimized the structure of aloperine and derived compounds with markedly improved activit...
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| Pubblicato in: | ACS Med Chem Lett |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2017
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5683702/ https://ncbi.nlm.nih.gov/pubmed/29152054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00376 |
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