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Aloperine and Its Derivatives as a New Class of HIV-1 Entry Inhibitors
[Image: see text] A quinolizidine-type alkaloid aloperine was found to inhibit HIV-1 infection by blocking HIV-1 entry. Aloperine inhibited HIV-1 envelope-mediated cell–cell fusion at low micromolar concentrations. To further improve the antiviral potency, more than 30 aloperine derivatives with a v...
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| 發表在: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Chemical
Society
2016
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4789664/ https://ncbi.nlm.nih.gov/pubmed/26985308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00339 |
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