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Shortened Penetratin Cell-Penetrating Peptide Is Insufficient for Cytosolic Delivery of a Grb7 Targeting Peptide

[Image: see text] Delivery across the cell membrane is of critical importance for the development of therapeutics targeting intracellular proteins. The use of cell-penetrating peptides (CPPs), such as Penetratin (P16), has facilitated the delivery of otherwise cell-impermeable molecules allowing the...

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Bibliographische Detailangaben
Veröffentlicht in:ACS Omega
Hauptverfasser: Watson, Gabrielle M., Kulkarni, Ketav, Brandt, Rebecca, Del Borgo, Mark P., Aguilar, Marie-Isabel, Wilce, Jacqueline A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2017
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5683694/
https://ncbi.nlm.nih.gov/pubmed/29152602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.6b00561
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